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Cardiovascular Risk Profile

(PLAC Test Included)

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Detect problems before they become troubles.

Our first line blood tests are specifically tailored to provide a picture of how various aspects of the body is functioning and performing.

 

  • PLAC test should help to identify hidden risk of cardiovascular event that might be missed by more conventional risk factors (eg cholesterol levles, blood pressure, family and smoking history). 

 

  • High levels are indicative of increased risk of heart attacks and strokes.

 

  • Imaging tests whilst able to assess the anatomical state of blood vessels, cannot identify plaque that is vulnerable to rupture. 

 

 

The PLAC test is recommended for clients with, but not limited to, two or more of the following risk factors:

  • Family History of Cardiovascular Disease

  • Diabetes

  • Obesity

  • Smoker

  • Males aged 65 and over

  • Females aged 55 or over

  • High Cholesterol

  • High Blood Pressure

  • Metabolic Syndrome

  • Chronic Kidney Disease

  • On lipid lowering treatment

  • High saturated fat diet 

  • Poor physical activity

 

This blood test profiles:

Cholesterol

Triglycerides
HDL Cholesterol

LDL CholesteroL

Apolipoprotein A Apolipoprotein B
Lipoprotein (a) Fibronogen
hsCRP Lp-PLA2 (PLAC Test)
Homocysteine  

 

 

PLAC Test

The PLAC test measures the amount of lipoprotein-associated phospholipase (Lp_PLA2) in blood. Lp-PLA2 is an enzyme primarily associated with low density lipoprotein (LDL). LDL carries Lp-PLA2 to the coronary artery walls where it activates an inflammatory response. If present, this causes plaque to become more prone to rupture. 

Because this enzyme is associated with causing inflammation of coronary artery walls, high levels of Lp-PLA2 would therefore seem to indicate an increased risk of heart attack or stroke. Given that the majority of heart attacks and strokes are caused by plaque rupture and thrombosis, individuals with high levels or Lp-PLA2 might benefit from more aggressive management with lipid lowering agents, therapeutic intervention and/or lifestyle changes. 

 

Traditional inflammatory markers, such as hsCRP, and CRP, whilst recognised as being useful systemic inflammatory markers are not as sensitive for identifying inflammation of the coronary artery walls. As a result, the PLAC Test, which is measuring levels of Lp_PLA2, serves as a specific independent coronary marker. 

  • Lp-PLA2 is independent of traditional cardiovascular risk factors
  • Lp-PLA2 is an enzyme produced in the plaque and its measurement is therefore more specific than other inflammatory markers.
  • Increases in Lp-PLA2 levels are not caused by traditional risk factors.
  • Imaging tests whilst able to assess the anatomical stat of blood vessels, cannot identify plaque that is vulnerable to rupture. 

 

Lp-PLA2 levels should help to identify hidden risk of cardiovascular event that might be missed by more conventional risk factors (e.g. cholesterol levels, blood pressure, family and smoking history). 

Lipid levels alone cannot provide a great deal of information on the status of the artery wall whereas Lp-PLA2 is a direct measure of artery wall enzyme activity, independent of other cardiovascular markers. It is intended that the PLAC test should replace blood lipid testing or other traditional risk factors identified for cardiovascular disease. It provides an additional independent risk marker. 

 

What is Included?

A Blood Profile Report including any measurements.

 

How do I Prepare for this Test?

  • No Preperation is required.

 

What Does The Blood Test Involve?

This blood test is just like a standard blood test.

You will be asked to uncover you left or right arm and suitable vein is found. A tourniquet will be placed and tightened around your upper arm allowing the veins to swell and a needle will be placed into your vein. A small quantity of blood is then drawn into tubes. Once the procedure is complete a small plaster will be placed onto the site which can be removed after a few hours. 

 

Note:

Blood results require interpretation. All results should be interpreted by your regular health care professional / GP.
We will  require details of your GP / Health Care Professional, which may be requested prior to or at the time of the service.

£269
Deposit Required At Booking.
Terms and Conditions apply.
Results in 4 Days Convenient Appointments Expert Advice No.1 First class service from the No.1 Clinic. Safety The World Health Organisation considers ultrasound to be very safe Location A Few Minutes Walk from Gants Hill Tube Station (Central Line) Parking Car Parking Available at Clinic. Pay & Display Opposite.

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