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Panorama NIPT test – Looking after your little treasure

Knowledge Hub

4 mins readFact Checked
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Written By:

Atif Riaz

Medically Reviewed By:

Mr M. Usman

Panorama NIPT

What is the Panorama NIPT test?

The Panorama NIPT test is one of the leading non-invasive prenatal pregnancy screening tests available for parents wishing to determine the probability of their baby having Down’s syndrome (Trisomy 21), Edwards’ syndrome (Trisomy 18) and Patau’s Syndrome (Trisomy 13). It can also screen for triploidy – a condition where a baby has an extra set of chromosomes for a total of 69 chromosomes instead of the usual 46.

This is a blood-based genetic, prenatal screening test of the pregnant person that screens for common chromosomal conditions that affect a baby’s health. Panorama uses SNP*-based technology to deliver highly accurate results and unique insights for both singleton and twin pregnancies.

When can the Panorama NIPT test be performed?

The test can be performed as early as nine weeks gestation. Most results will be returned to your doctor within 5-7 calendar days. It is available for single including donor or surrogate and twin pregnancies. You can also choose to find out the sex of your baby*.  

What will the test show?

Panorama NIPT is a screening test, which means that this test does not make a final diagnosis. A high risk result means that your pregnancy has a higher chance of having a specific genetic condition. However, you cannot know for sure if your baby has that condition based upon the screening result alone. All medical decisions should be made after discussion with your healthcare provider regarding diagnostic testing during the pregnancy, like chorionic villus sampling (CVS) or amniocentesis, or testing the baby after birth.

Panorama NIPT uses SNP (single nucleotide polymorphism – the 1% of our DNA that makes us different from one another) based technology to deliver highly accurate results. It has been validated in the largest prospective NIPT study ever and is the only test.

Panorama NIPT Mother-Baby DNA Diagram

How is the test carried out?

The test involves a simple and safe blood test where a small quantity of blood is collected from the mother usually via a vein in her arm. The blood is then sent to the lab and analysed for cell free DNA (cfDNA), circulating fragments of fetal DNA. These are derived from the maternal placenta, the organ providing nutrition to baby, and are circulating in the mother’s blood stream. The results determine if there is a high or low probability of baby having one of the 3 screened conditions; Down’s syndrome, Edwards’ syndrome and Patau’s syndrome. 

Where are the test samples analysed?

The test is processed and analysed in the USA, therefore the results are available a few days later than other NIPT tests due to the transport time required.

What are the key differences with the Panorama NIPT test?

Panorama has a higher positive predictive value as compared to the combined test which means lower high probability results where the condition is not actually present.

The Panorama Test can be performed for the majority of pregnant women, however is particularly recommended for

  • parents who wish to avoid unnecessary invasive testing which carries a risk of miscarriage
  • women over 35 years of age
  • parents that have had a high probability result in their current or previous pregnancies 
  • confirmed chromosomal condition in a previous pregnancy

Please note that blood thinners can increase the possibility of receiving no results.

*Please note in some instances the NIPT test may not be able to determine the sex.  In monochorionic (identical) twin pregnancies NIPT test can confirm the sex of each twin as it will be the same. For dichorionic (non identical) twin pregnancies NIPT can confirm if there are 2 girls, but can only confirm the presence of 1 boy.

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The Scan Clinic is committed to providing accurate and objective educational content about health and medical related topics. We know that there is a lot of misinformation out there, and we take our responsibility to be a trustworthy source of information seriously. Every article on our site is thoroughly fact-checked by our team of writers.

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