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Neo 24

Non Invasive Prenatal Test

When can I have this?

10+ weeks

What's included?

  • Performed from 10 weeks of pregnancy onward
  • 24 Fetal Chromosones analyed
  • Trisomy 21 (Down syndrome)
  • Trisomy 18 (Edwards syndrome)
  • Trisomy 13 (Patau syndrome)
  • Optional Gender Identification
Regular Price £599
Full Payment at booking.
Terms and Conditions apply.

Book Now

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Award Winning First class service from multi award winning clinic. Trusted Our experts are trusted by midwives, doctors and many different health professionals Convenient Convenient appointments to fit your schedule with our experts Rated Excellent rating on Google and WhatClinic Featured Featured in multiple publications including Huffington Post.

Neo 24

Non Invasive Prenatal Test

When can I have this?

10+ weeks

What's included?

  • Performed from 10 weeks of pregnancy onward
  • 24 Fetal Chromosones analyed
  • Trisomy 21 (Down syndrome)
  • Trisomy 18 (Edwards syndrome)
  • Trisomy 13 (Patau syndrome)
  • Optional Gender Identification

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What's Included:

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Neo24 identifies more than 99% of pregnancies affected with Down syndrome.

✔ Neo24 analyses 24 foetal chromosones from mothers blood.

✔ Neo24 reports to have the highest sensitivity of any prenatal screening test for the detection of commonly screened chromosomal abnormalities: trisomy 21, trisomy 18, and trisomy 13..

✔ Results may take 8-12 days due to delays in processing caused by COVID-19

✔ This cutting edge, highly accurate test is not routinely available in the mainstream NHS maternity service. 

✔ Early Viability Dating Scan with Report

Neo24 Blood test with Risk Results

✔ 2 Free 2D Pictures

✔ No GP Referral Needed at London's Premier Clinic

 

Neo24 Test Criteria:

Pregnancy must be

  • Viable and at least 10 weeks pregnant.
  • Single or twin pregnancy only. 
  • Validated for natural conception or IVF conception using your eggs or a donor egg.
  • If you have a high BMI there is a small chance of not having enough fetal fraction from the test in which case a repeat test is advised in 2-3 weeks at no additional cost.

 

 

Ineligibility Criteria:

  • Women carrying 3 or more babies (triplets and above).
  • Women who have used an egg donor or surrogate carrying more than one baby (twins or triplets).
  • Women who have received an organ transplant.
  • Women who have received a bone marrow transplant.
  • Women who have metastatic cancer

 

 

What is the Neo24 Test?

Neo24 is a Non-invasive Prenatal Screening test produced by Juno Genetics for specific genetic conditions.

 

Every pregnant mother to be will have her own DNA in her bloodstream as well as the DNA of your unborn baby. Your babies DNA is found in your blood in the form of short fragments circulating around called cell-free DNA fragments (cfDNA). Neo24 test analyses this cfDNA to calculate a probability score of your baby having one of the three screened conditions; Down’s syndrome (known as Trisomy 21), Edwards’ syndrome (known as Trisomy 18) and Patau’s syndrome (known as Trisomy 13).

 

The Neo24 test claims to be able to provide results where there is a very low foetal fraction (less than 4%), which is something no other prenatal screening test can.​

 

 

What is Down's syndrome?

Down’s syndrome, also known as Trisomy 21, is a congenital disorder arising from a chromosomal defect during fetal development which causes various physical and mental disabilities. Down's syndrome is typically not inherited - it's a simple the result of a one-off genetic change in the sperm of egg. In every pregnancy, there is a small chance of having a child with Down's syndrome, but the likelihood increases with the age of the mother.

 

 

How is the Neo24 test performed and analysed?

The Neo24 blood test involves taking a blood sample from the mother, just like a routine blood test. The mother must be at least 10 weeks into her pregnancy.

The blood sample is sent and analysed in a specialist laboratory where next-generation sequencing technology, coupled with advanced bioinformatics analysis will detect free-floating fetal DNA (cfDNA), which is a marker in the mother's blood of baby's DNA. The resultant information will be generated into a detailed risk analysis report. 

 

It has been reported that 1 in 30 women can be given a high result with the NHS combined screening and are advised to undergo an invasive testing such as amniocentesis or chorionic villus sampling (CVS) to determine baby's chromosomal structure. These procedures carry a 1% risk of miscarriage. NIPT is a perfect risk-free alternative as there is no risk of miscarriage from non-invasive test. 

 

While the Neo24 test or any other NIPT is NOT classed as a diagnostic test like amniocentesis or CVS it will seek to reassure you that you are making the right choices should you need further testing.

 

 

What is the primary purpose of this test?

An ultrasound scan is performed in conjunction with the test to confirm fetal viability, how far along the pregnancy is, and if the mother is having twin or multiple babies. We can also provide an estimated due date.

This test is performed to assess the risk of certain chromosomal defects including Trisomy 21 (Down's syndrome), Trisomy 18, Trisomy 13.

The test can also check the sex of your baby (optional).

 

 

 

What if I am having twins?

The Neo24 test can be used for twin pregnancy.  It can even be used if the pregnancy is conceived with donated eggs.

It can not be performed for triplets/multiple pregnancies. 

 

 

What problems will this test not detect?

This test will not be able to detect structural abnormalities such as spina bifida, heart defects and growth problems. 

 

 

Your Results

 Results for your test will be available in 8-12 days due to delays in processing caused by COVID-19.

 

The Neo24 test results take into account your age, pregnancy gestation and the DNA fraction in the blood sample. The results are shown on a report in a graphical format as either "low or high" risk for the different the trisomies. 

 

The Neo24 test is a screening test. A screening test is one that is performed to identify those that are at higher risk or more likely to develop a specified disease or condition. It can not however provide confirmation and therefore those identified as having higher risk may need further diagnostic tests.  A diagnostic test is a procedure that can identify a specific condition, disease or illness. 

 

This test screens for Down's syndrome as well as a few other genetic conditions. Therefore this test will give you information about the risk your baby has for these specific conditions. 

 

As with all screening tests, false-positives and false negatives may occur however these are much lower in this test as compared to traditional tests available.

Should you have a high-risk result you have the option for further diagnostic tests such as amniocentesis or chorionic villus sampling.

 

 

Does the Neo24 blood test ever need to be repeated?

Occasionally there is insufficient fetal DNA in the blood sample obtained from mother to obtain a result. Therefore a repeat sample would be needed to be collected. This occurs in about 2% of tests with overall no result rate of 3% (2% due to insufficient fetal fraction and 1% due to other reasons). 

If there is no result from your initial test we would offer one free re-test. 

 

 

What is Included?

Neo24 Blood test including Viability & Dating Ultrasound Scan with a report and any measurements.

 

 

How do I Prepare for this Test?

  • A full bladder may be required for this pregnancy scan, therefore, please drink 0.5 litres of fluid approximately 30 minutes before your scheduled appointment and please try your best not to empty your bladder before the examination. 

  • An internal scan may be needed particularly in the early stages of your pregnancy. This may be offered at the start of the appointment instead of the scan over your tummy as it may give better information..

  • Please bring along any information / medical notes/reports which are concerning the pregnancy as they may provide useful information for the scan.
  • We will require details of your GP / Health Care Professional, which may be requested before or at the time of the service.

 

 

 

Please note

  • Please bring your pregnancy book with previous scan results to your appointment as we will not be able to scan you without them.
  • All scans are performed to accomplish the main objective only.
  • Sometimes at the scan, we may not detect the heartbeat or can visualise the fetus on the screen. In such instances, this could be because it's too early for the ultrasound scan to detect the pregnancy or could indicate that a miscarriage has occurred. In the event of this happening, please be reassured that our trained staff are on hand to offer advice and guidance on next steps. 
  • The test can only be performed from 10 weeks gestational age. If the scan determines your pregnancy is earlier than 10 weeks you will be invited to book the Neo24 blood test at the next available appointment when you are at least 10 weeks pregnant. 
  • Single ultrasound scan is included however any additional scans that may be required would be charged at £79 each.
  • Gender Determination is based on the Neo24 DNA-blood test and is not conducted by ultrasound. There is no additional fee if this option is required.   
  • This ultrasound scan may involve internal scanning.
  • We may require details of your GP / Health Care Professional which will be requested from you before or at the time of your scan.
  • Our pregnancy scans do not replace or substitute any scan you have or will have with the NHS / maternity care provider.
Regular Price £599
Full Payment at booking.
Terms and Conditions apply.

Book Now

Call Me

Locations

Award Winning First class service from multi award winning clinic. Trusted Our experts are trusted by midwives, doctors and many different health professionals Convenient Convenient appointments to fit your schedule with our experts Rated Excellent rating on Google and WhatClinic Featured Featured in multiple publications including Huffington Post.