Make a Booking


Non Invasive Prenatal Test (NIPT)

Dating Viability Ultrasound Scan

(Not Currently Available - Coming Soon)


Blood_test_icon.png Report_icon.png Scan_icons.png b&w_pics_2_icon.png


 Harmony Prenatal Test is one of the most accurate non invasive DNA-based blood screening test for Down's Syndrome.

 Harmony Test has over 99% sensitivity for detection of Down's Syndrome, much more than traditional tests such as combined screening routinely offered.

 Harmony Prenatal Test can be performed from 10 weeks.

 Gender determination is optional and at no additional cost

 Results normally take 5 days

 This cutting edge, highly accurate test is not routinely available in the mainstream NHS maternity service. 


 Early Viability Dating Scan with Report

✔ Harmony Blood test with Risk Results

✔ 2 Free 2D B&W Pictures

✔ No GP Referral Needed at London's Premier Clinic


What is the Harmony Test?

The harmony test is one of the leading non invasive prenatal screening tests with incredibly high sensitivity for detecting Downs syndrome (a congenital disorder arising from chromosomal defect causing various physical and mental disability). 

The Harmony test involves taking a blood sample from the mother who is at least 10 weeks into her pregnancy. The blood sample is analysed for cell free DNA, a marker in the mother's blood of baby's DNA. The test has over 99% sensitivity for the detection of Downs syndrome, 97.4% of Edwards syndrome and 93.8% of Patau's syndrome. It has a false positive rate of less than 0.1% which reduces the need for invasive testing by CVS or amniocentesis, both of which carry a 1% risk of miscarriage. 

A scan is also performed in conjuction with the test to confirm fetal viability, how far along the pregnancy is, and if the mother is having twin or multiple babies. We can also provide an estimated due date.

The Harmony test can be used to check twins with a 95% sensitivity for detection of Downs syndrome. It can even be used if the pregnancy is conceived with donated eggs.


What is the Downs syndrome?

Downs syndrome, also known as Trisomy 21, is a congenital disorder arising from a chromosomal defect during fetal development which causes various physical and mental disabilities. Down's syndrome is typically not inherited - it's simple the result of a one off genetic change in the sperm of egg. In every pregnancy there is a small chance of having a child with Down's syndrome, but the likelihood increases with the age of the mother.


What problems will this test not detect?

This test will not be able to detect structural abnormalities such as Spina Bifida, heart defects and growth problems. 


What is purpose of the Harmony Test & Scan?

The Harmony Test is a DNA based Non Invasive Prenatal Test to screen for Down's syndrome. Down's syndrome, also known as Down syndrome or trisomy 21, is a genetic condition that typically causes some degree of learning disability and certain physical characteristics. It is regarded as the most accurate screening test available for Down's Syndrome as compared to other traditional tests such as combined screening, which is currently the main method of screening for Down's syndrome offered in the mainstream NHS.   

The Harmony test involves a simple blood test, just like a routine blood test, whereby we will collect a small sample of venous maternal blood taken from mummys arm. A scan is also performed in conjuction with the test to determine fetal viability, fetal gestational age (how far along the pregnancy is),  location of pregnancy, single / multiple babies & estimated due date (EDD).

The sample is sent to a specialist Laboratory where next generation sequencing technology, coupled with advanced bioinformatics analysis will detect free floating fetal DNA (cfDNA) in the mothers blood. 

The resultant information will be combined with the information from your ultrasound scan and generate a detailed risk analysis report.  The whole process takes approximately 10 days.


Currently this cutting edge technology is not available in mainstream NHS services and there are only a handful of Laboratories and Clinics offering it.


This is a relatively new highly accurate alternative to the Downs Syndrome Screening Service provided by the NHS. It has been reported that 1 in 30 women can be given a high result with the NHS combined screening and are advised to undergo an invasive testing such as amniocentesis or chorionic villus sampling (CVS) to determine baby's chromosomal structure. These procedures carry a 1% risk of miscarriage. NIPT is a perfect risk free alternative as there is no risk of miscarriage from this non-invasive test. Furthermore NIPT carries the best detection rate of all screening tests and will detect over 99.5% of babies affected with Down's syndrome and other chromosomal abnormalities and less than 1 in 3000 women will be given high risk (false positive) screening test results. 

Whilst Harmony or any other NIPT is NOT classed as a diagnostic test like amniocentesis or CVS it will give you the reassurance to the highest degree possible that you are making the right choices should you need further testing. 

What is Included?

A Scan & Blood test including Reports and any measurements.


How long will the results take?

Your blood will be transported to a UK based Harmony Approved pathology laboratory where they will be analysed and reported. Therefore the results for your test will be available in 5-7 days. 


Your Results

The Harmony test is a screening test. A screening test is one that is performed to identify those that are at higher risk  or more likely to develop a specified disease or condition. It can not however provide confirmation and therefore those identified as having higher risk may need further diagnostic tests.  A diagnostic test is a procedure that can identify a specific condition, disease or illness. 

This test screens for Down's syndrome and two other genetic conditions, trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome).  Therefore this test will give you information about the risk your baby has for these specific conditions. 

As with all screening tests, false-positives and false negatives may occur however these are much lower in this test as compared to traditional tests available.

Should you have a high risk result you have the option for further diagnostic tests such as amniocentesis or chorionic villus sampling


How do I Prepare for this Test?

  • A full bladder may be required for the early pregnancy scan therefore please drink 1 litre of fluid approximately 1.5 hours before your scheduled appointment and please try your best not to empty your bladder before the examination. An internal scan may also be required for this service.
  • Please bring along any information / medical notes / reports which are in relation to the pregnancy as they may provide useful information for the scan.
  • We will  require details of your GP / Health Care Professional, which may be requested prior to or at the time of the service.


What Does The Blood Test Involve?

This blood test is just like a routine standard blood test.


Please note

  • Sometimes at the ultrasound scan, we may not detect the heartbeat or visualise the fetus on the screen. In instances where we’re unable to do so, this may simply be because it's too early for the ultrasound to be conducted successfully or could indicate that a miscarriage has occurred. In the event of this happening, we’d advise that you arrange for a follow-up scan at a later date, which can be arranged at The Scan Clinic.
  • Please bring your pregnancy book / previous scan results to your appointment. 
  • All scans are carried out with the aim to accomplish the main objective only.
  • This test is only available for single or twin pregnancy.
  • The test can only be performed from 10 weeks gestational age. If the scan determines your pregnancy is earlier than 10 weeks you will be invited to book the Harmony blood test at the next available appointment when you are at least 10 weeks pregnant. 
  • Single ultrasound scan is included however any additional scans that may be required would be charged at £79 each.
  • Gender Determination is based on the Harmony DNA-blood test and is not conducted by ultrasound. There is no additional fee if this option is required.   
  • We will require details of your GP / Health Care Professional; this will be requested from you prior to or at the time of your scan.
  • This ultrasound scan may involve internal scanning.
  • Our pregnancy scans does not replace or substitute any scan you have or will have with the NHS / Regular health provider.

Related Services

We offer a wide range of pregnancy ultrasound scans as well as blood profiles, please feel free to have a look over the complete range by following the quicklinks below.




Deposit Required at booking.
Terms and Conditions apply.
Fast Results Convenient Appointments Expert Advice No.1 First class service from the No.1 Clinic. Safety The World Health Organisation considers ultrasound to be very safe Location A Few Minutes Walk from Gants Hill Tube Station (Central Line) Parking Car Parking Available at Clinic. Pay & Display Opposite.

Book now

Call Me

Refer Patient